 |
||||||
 |
 |
 |
 |
 |
 |
|
Statistical analysis applied to genome
and proteome analyses
 |
 |
|---|---|
|
|
 |
 |
|
Schedule and teachersLocation: rooms INR219 (theory) and INN218 (exercises)
|
| Time | Topic | Teacher |
| Mo Feb 04 | DAY 1 | |
| 08:45 - 09:00 | Welcome |
Laurent Falquet |
| 09:00 - 12:30 | Theory: - Differential gene expression, power and linear models. - Exploratory unsupervised analyis. |
Mauro Delorenzi |
| 13:30-17:30 | Exercises: Computer Lab with R. Review: use of R Case study PCA and clustering |
Mauro Delorenzi Eugenia Migliavacca Thierry Sengstag |
| Tu Feb 05 | DAY 2 | |
| 08:30 - 12:00 | Theory: - Class discrimination for microarray studies. - Analysis of multiple datasets and public databases. |
Vlad Popovici Pratyaksha Wirapati |
| 13:30-17:30 | Exercises: Computer Lab with R Case study on Predictive gene signatures |
Vlad Popovici Pratyaksha Wirapati Nadine Zangger |
| 19:30 | Social Dinner (map) | |
| We Feb 06 | DAY 3 | |
| 09:30 - 10:20 | USGEB plenary session: Evolution of Cooperation in Ant and Robot Societies |
Room SG1 L. Keller (UNIL-CH) |
| 11:00 - 12:30 | Theory: From Singular Value Decomposition to modular analysis of gene expression data |
Sven Bergmann |
| 13:30-14:45 | Exercises: Computer Lab to modular analysis |
Sven Bergmann Bastian Peter Gabor Csardi |
| 15:00 - 16:15 | USGEB plenary session: Designing Biological Systems Robustness And Scaling In Developmental Patterning |
Room SG1 P. Silver (Harvard Med. School, USA) N. Barkai (Weizmann Inst., Israel) |
| 16:30-17:30 |
Free time* |
|
| Th Feb 07 | DAY 4 | |
| 09:00 - 10:15 | USGEB plenary session: Studying Biomechanics To Gain Insight Into Sensory Perception Lymphatic Biology And Interstitial Flow: Roles In Cancer Metastasis And Immunity |
Room SG1 M. Hartmann (Northwestern U.-USA) M. Swartz (EPFL-CH) |
| 11:00 - 12:30 | Theory: Genetic association studies: Introduction to the analysis of whole-genome SNP-array data |
Sven Bergmann |
| 13:30-14:45 | Exercises: Computer Lab to Genetic association studies |
Toby Johnson Zoltán Kutalik Alain Sewer |
| 15:00 - 16:15 | USGEB plenary session: Quantify What Cannot Be Measured: Small Molecule Fluxes Through Metabolic Networks Biology As Reverse Engineering: A Few Examples |
Room SG1 U. Sauer (ETHZ-CH) S. Leibler (The Rockefeller U.-USA) |
| 16:30-17:30 |
Free time* |
|
| Fr Feb 08 | DAY 5 | |
| 08:30 - 12:00 | Theory: Motif identification with position dependent weight matrix Estimating background models and score distributions |
Félix Naef |
| 13:30-15:30 | Exercises: Computer Lab with R |
Félix Naef Guillaume Rey Bernhard Sonderegger |
| 16:00-17:30 |
Free time* End of the course. Farewell. |
|
| * Time is given to the participants to finish their exercises, complete their reports or analyze their own data in the computer room |
|