Prediction of Transmembrane Regions and Orientation
The TMpred program makes a prediction of membrane-spanning regions and their orientation. The algorithm is based on the statistical analysis of TMbase, a database of naturally occurring transmembrane proteins. The prediction is made using a combination of several weight-matrices for scoring.
K. Hofmann & W. Stoffel (1993)
TMbase - A database of membrane spanning proteins segments
Biol. Chem. Hoppe-Seyler 374,166
For further information see the TMbase documentation.
Usage: Paste your sequence in one of the supported formats into the sequence field below
and press the "Run TMpred" button.
Make sure that the format button (next to the sequence field) shows the correct format
Choose the minimal and maximal length of the hydrophic part of the transmembrane helix